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Researchers in Queensland have achieved a groundbreaking milestone by using human stem cells to produce fully functioning skin tissue in a laboratory setting. Led by the University of Queensland’s Frazer Institute and Herston Biofabrication Institute, the generated skin tissue can develop hair follicles, neurons, sebaceous, and sweat glands. This innovative approach, utilizing induced pluripotent stem cells converted into skin organoids, offers a more accurate representation of human skin than existing substitutes. Dr. Abbas Shafiee, the project leader, highlights the potential of this advancement in improving treatments for severe burns and wounds, ultimately enhancing patients’ quality of life. Professor Kiarash Khosrotehrani emphasizes the transformative impact on wound care, disease modeling, and hair transplantation. The research aims to progress towards translational studies, paving the way for clinical applications in the future.

Keywords: organoids, skin organoids, skin tissue, lab-grown skin