Lipid Molecules Revolutionise Organoid Architecture for Disease Modelling
Journal: Cell reports
Author: Andrew M. Tidball et al., USA
Researchers discover that lipid molecules LPA and S1P can flip organoid orientation from inside-out to outside-in, mimicking natural tissue structure across brain, lung, and intestinal models.
Three-Dimensional Breakthrough Transforms Skin Cells Into Brain-Ready Neurons
Journal: Science Advances
Author: Janko Kajtez et. al, Sweden
Scientists develop 3D culture method that transforms adult skin cells into functional neurons more efficiently, with successful brain transplantation opening new regenerative therapy possibilities.
Protein Partnership Unlocks Secrets of Stem Cell Fate Decision-Making
Journal: Stem Cell Reports, ISSCR
Author: Duo Wang et. al, USA
Study reveals how GSK3α protein controls GSK3β activity in embryonic stem cells, providing new insights into maintaining the delicate balance between cell renewal and specialisation.
Spatial Biology Maps the Cellular Orchestra Behind Ageing Muscle Repair
Journal: Nature Communications
Author: Jonas Brorson et. al, Denmark
Advanced spatial analysis reveals how specific cell types and immune signals coordinate muscle repair in elderly humans, identifying potential targets for age-related regenerative decline.
