Light-Controlled Cancer Therapy Through Lipid Droplet Manipulation
Journal: Trends in Biotechnology
Author: Qingjie Bai et al. China
Scientists engineer optogenetic systems to cluster cancer cell lipid droplets using blue light, disrupting mitochondrial energy supply and suppressing tumour growth both in laboratory and living models.
Divide-and-Conquer Bone Healing with Engineered Organoids
Journal: Nature Communications
Author: Xianzhu Zhang et al. China
Researchers develop ossification centre organoids that rapidly bridge critical bone defects by recruiting specific stem cell populations, mimicking natural bone development through strategic implantation.
Precision Base Editing Rescues Disease in Living Mice
Journal: Aaron Schindeler et al., Australia
Author: Molecular Therapy, Nucleid Acids
A comprehensive review reveals CRISPR base editing successfully corrects genetic diseases in 66 mouse studies, extending survival and restoring function across diverse conditions from muscular dystrophy to neurodegeneration.
