Cardiac organoids replicate the cellular diversity and functional structures of the heart, displaying spontaneous contractility and electrical activity akin to the natural heart.
They serve as valuable models for studying cardiac physiology, disease mechanisms, and drug responses.
Researchers can apply genetic modifications to study specific genes and pathways related to heart development and diseases.
Cardiac organoids play a crucial role in advancing our understanding of cardiac biology, providing a platform for drug testing and potential therapeutic developments in a controlled in vitro setting.
Cardiac organoid
Toxicology is a significant factor contributing to the attrition in the development of therapeutic drugs, and it is a crucial consideration when selecting candidate drugs to progress through the development pipeline.
Cell Type
· iPSC
Assay
· Toxicity test
Cardiac organoids have electrophysiological properties similiar to cardiac tissue
Lambda Biologics GmbH
Deutscher Pl. 5c, 04103 Leipzig, Germany
