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Absorption

To gauge the extent of drug absorption relevant to an actual person, organoids are utilized to measure the degree of drug absorption to ensure its usability.

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Starting cost

Absorption

€4.000+

Lambda provides drug absorption evaluation through drug (sample) permeability analysis
using hPSC-derived human functional intestinal epithelial cells (hIEC).

Cell Type

· iPSC

Organoid type

· Intestinal organoid

Assay

Drug Absorption Assay(2D)

Lambda provides drug absorption evaluation through drug (sample) permeability analysis using hPSC-derived human functional intestinal epithelial cells (hIEC).

Assay process

Technical

Comparison of predicted fraction absorbed by the human intestine of six model compounds in functional hIEC and Caco-2 cell system.

Functional hIECs can better predict the absorption and extent of oral bioavailability in humans.