Utilizing artificially cultured skin models that closely mimic human skin, various skin evaluation tests are conducted, following OECD guidelines. These models offer an ethical and controlled environment to assess the efficacy, safety, and other properties of skincare or cosmetic products without the need for human or animal experiments.
Our full-thickness skin model is a meticulously reconstructed 3D in vitro model replicating both the epidermis and dermis. It plays a crucial role in predicting drug efficacy by simulating the interaction between the epidermis and dermis.
Skin efficacy test
The full-thickness skin model offers the advantage of observing proteins beyond those in traditional epidermal models, including dermal proteins and those between the epidermis and dermis.
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Starting cost
Assay process
Readout
Top mutated genes
Assess the approximate external appearance condition (visual reaction according to the substance)
OCT observation
Confirming the approximate reaction of the substance on OCT (Optical Coherence Tomography) (including epidermal formation and tissue thickness)
H&E staining
Detailed examination of skin cell condition compared to OCT
Quantification of stratum corneum and cell layer thickness in the epidermis
Immunofluorescence staining
Expression status and expression level comparison of the requested antibody.